Search results for "Cocaine use"

Rolling Psychodynamic Group for Cocaine Use Disorder: A Single-Group Study Using Multilevel Models

2017

Cocaine disorder has been shown to have an important impact on the success of treatments because it is often associated with social or occupational impairment, high relapse incidences and poor trea...

Quality of life, needs, and interest among cocaine users: differences by cocaine use intensity and lifetime severity of addiction to cocaine.

2010

We examined the quality of life (QoL) of 149 patients who were recruited in 2005 at outpatient treatment centers for cocaine dependence in Spain. Important life areas and life areas with potential need and interest to change in order to improve the QoL were analyzed in terms of patients? cocaine use intensity within the previous six months and lifetime severity addiction to cocaine. The Spanish versions of the Drug User Quality of Life Scale and the Lifetime Severity Index for Cocaine were used to measure QoL, needs and interest, and severity addiction to cocaine. The data analysis employed t-tests, linear regression, Mann?Whitney U tests, multivariate regression, and chi-square tests. Tail…

Ulcerative pyoderma gangrenosum associated with cocaine use

2020

Bilateral Transcranial Magnetic Stimulation of the Prefrontal Cortex Reduces Cocaine Intake: A Pilot Study

2016

Background Chronic cocaine consumption is associated with a decrease in mesolimbic dopamine transmission that maintains drug intake. transcranial magnetic stimulation (TMS) is gaining reliability, a useful therapeutic tool in drug addiction, since it can modulate cortico-limbic activity resulting in reduction of drug craving. Aims In the present study, we investigated the therapeutic effect of bilateral TMS of prefrontal cortex (PFC) in reducing cocaine intake, in a sample of treatment-seeking patients with current cocaine use disorder (DSM-V). Methods Ten cocaine addicts (DSM-V) were randomly assigned to the active or sham stimulation protocol in a double-blind experimental design. Twelve …

Investigación española en las áreas de adicciones y de trastornos de la alimentación: análisis de la producción, colaboración e impacto científico (1…

2021

Las adicciones y los trastornos de la alimentación constituyen uno de los principales problemas de salud en la sociedad contemporánea al que se destinan gran cantidad de recursos destinados a la investigación para su prevención y tratamiento. Objetivos. Analizar la investigación española en el área de adicciones y trastornos de la alimentación desde que se publicó el primer trabajo recogido en bases de datos bibliográficas y desde una perspectiva bibliométrica. Metodología. Para obtener la información necesaria se consultaron las bases de datos Web of Science, Scopus y bases de datos del CSIC. Se elaboró un perfil de búsqueda específico. Se obtuvieron indicadores bibliométricos de producció…

Characterization and enhancement of resilience to the effects of social stress on the rewarding properties of cocaine in male mice

2022

El principal foco de interés en la presente Tesis Doctoral es estudiar la resiliencia a desarrollar un trastorno por consumo de cocaína tras la exposición a estrés. Para ello utilizamos modelos animales de estrés social (la derrota social repetida intermitente, DSRI) y de efectos reforzantes de las drogas (el paradigma de Condicionamiento de Preferencia de Lugar, CPL), ya que en estudios previos hemos demostrado que la exposición a DSRI incrementa los efectos reforzantes de la cocaína en el CPL (García-Pardo y cols., 2019; Calpe-López y cols., 2020). Nuestro objetivo es identificar a los animales resilientes a este efecto de la DSRI, caracterizar su comportamiento tras el estrés, estudiar s…